NOVEL MOLECULAR HALLMARKS OF GROUP 3 MEDULLOBLASTOMA BY SINGLE-CELL TRANSCRIPTOMICS


A conceptual model for translating omic data into clinical action

Genomic, proteomic, epigenomic, and other "omic" data have the potential to enable precision medicine, also commonly referred to as personalized medicine.The volume and complexity of omic data are rapidly overwhelming human cognitive capacity, requiring innovative approaches to translate such data into patient care.Here, we outline Luster Dust a co

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Neutrophil Extracellular Traps Caused by Gut Leakage Trigger the Autoimmune Response in Nonobese Diabetic Mice

Increased formation of neutrophil extracellular traps (NETs) is associated with gut leakage in type 1 diabetes (T1D).To explore the mechanism of how enteropathy exacerbated by NETs triggers pancreatic autoimmunity in T1D, we carried out a correlation analysis for NET formation with gut barrier functions and Benches autoimmunity in nonobese diabetic

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